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Abstract

Genetic testing has opened new doors into understanding a patient’s future health. The human genome is extremely vast and complicated. Testing an entire genome for the innumerable genetic variants that have a bearing on the development of cancer is costly both in time25 and efficiency. Testing for just a single gene results in seeing a whole group of variations, which may or may not be pathogenic11. Pathogenic, in this case, is defined as a variant known to cause or increase risk of a disease, the degree of which is determined by how co-segregated it is with the disease16,17. One of the genes that is examined when looking at hereditary diffuse gastric cancer (HDGC) often is Cadherin-1, or CDH1.

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James_Stephenson_thesis_final_revision.pdf
19 Jul 2022
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Metadata

  • Advisor
    • Dr. Nancy Dalman

  • Department
    • Biology

  • Date submitted

    19 July 2022

  • Qualification level
    • Honor's/Undergraduate

  • Keywords